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I-Cytochrome C Isisombululo se-Deebio kwii-histanoxia ezahlukeneyo


  • INOMBOLO YECAS.:9007-43-6
  • IKHOWUDI ye-HS:3001.2000.90
  • Inkonzo Yefayile:IsiTshayina-GMP, iDMF
  • Pharmacopoeia umgangatho: CP
  • Iinkcukacha zeMveliso

    Iithegi zeMveliso

    Amava olawulo lweeprojekthi ezizizityebi ngokwenene kunye nomntu kwimodeli enye yoncedo yenza ukubaluleka okuphezulu konxibelelwano lwenkampani kunye nokuqonda kwethu ngokulula okulindelweyo kwiCytochrome C Isisombululo seDeebio kwiihistanoxia ezahlukeneyo, abathengi bethu basasazwa ikakhulu kuMntla Melika, eAfrika naseMpuma. IYurophu.siya kukhupha iimpahla ezikumgangatho ophezulu sisebenzisa ixabiso lokuthengisa elinobundlongondlongo.
    Amava olawulo lweeprojekthi ezityebileyo kunye nomntu okwimodeli yoncedo enye yenza ukubaluleka konxibelelwano lwenkampani kunye nokuqonda kwethu ngokulula okulindelekileyoezahlukeneyo histanoxia Cytochrome C, Isabelo sethu semarike sempahla yethu sinyuke kakhulu ngonyaka.Ukuba unomdla kuso nasiphi na isisombululo sethu okanye ungathanda ukuxoxa ngomyalelo wesiko, khumbula ukuba uzive ukhululekile ukuqhagamshelana nathi.Besijonge phambili ekwenzeni ubudlelwane beshishini obuyimpumelelo kunye nabathengi abatsha kwihlabathi liphela kungekudala.Sijonge phambili kumbuzo wakho kunye ne-odolo.

    Iinkcukacha

    1. Abalinganiswa: Isisombululo esicacileyo esibomvu esimnyama.

    2. Umthombo: Intliziyo yehagu.

    3. Inkqubo: I-Cytochrome C Isisombululo sikhutshwe kwintliziyo ye-porcine enempilo.

    4. Izibonakaliso kunye nokusetyenziswa: I-Cytochrome C Isisombululo sisetyenziswa njenge-adjuvant yonyango lokuqala lwe-histanoxia eyahlukeneyo, njengetyhefu ye-carbon monoxide, i-hypnotic drug poisoning, i-cyanide poisoning, i-neonatal suffocation, i-anaerobic phase yokutshatyalaliswa, ingozi ye-cerebrovascular, i-concussion sequela, i-dyspnea ebangelwa. I-anesthesia kunye nezifo zemiphunga kunye ne-myocardial ischemia ebangelwa zizifo ezahlukahlukeneyo zentliziyo. Icandelo le-electron transport chain kwi-mitochondria, i-cytochrome c ithathwa njengeyinkimbinkimbi esebenzayo esetyenziswa kwi-low-level laser therapy (LLLT), eyandisa umsebenzi we-metabolic kwaye ikhulula amandla amaninzi kwiiseli ukulungisa izicubu.Ibonisa umsebenzi we-peroxidase nge-oxidation yabaxhasi be-electron abahlukeneyo njenge-2,2-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) (ABTS), i-2-keto-4 -thiomethyl butyric acid kunye ne-4-aminoantipyrine.Isetyenziswe njengomlamli obalulekileyo kwiindlela ze-apoptotic.

    Kutheni sisi?

    Upase iGMP yaseTshayina

    · Iminyaka engama-27 yembali ye-enzyme yebhayoloji ye-R&D

    ·Imathiriyeli ekrwada iyalandeleka

    ·Thobela iCP kunye nomgangatho wabathengi

    ·Thumela ngaphandle kumazwe angaphezu kwama-30 kunye nemimandla

    ·Unamandla olawulo lwenkqubo esemgangathweni efana ne-US FDA, Japan PMDA, South Korea MFDS, njl.

    Inkcazo

    Izinto zovavanyo

    CP

    Abalinganiswa

    Isisombululo esicacileyo esimnyama esibomvu

    Ukuchongwa

    Iyahambelana

    Iimvavanyo

    Intsimbi

    0.40%~0.46%

    I-endotoxin yebhaktheriya

    <5.0EU/mg

    Uvavanyo lokwaliwa

    Iyahambelana

    Umsebenzi

    ≥ 95%

    Umxholo

    ≥ 15mg/ml

    Ukungcola kweMicrobial

    TAMC

    ≤ 100cfu/g

    I-TYMC

    ≤ 100cfu/g

    E.coli

    Iyahambelana

    Salmonella

    Iyahambelana

    I-Cytochrome C Solution isetyenziswa njenge-adjuvant yonyango lokuqala lwe-histanoxia eyahlukeneyo, efana netyhefu ye-carbon monoxide, ityhefu ye-hypnotic, i-cyanide poisoning, i-neonatal suffocation, i-anaerobic phase, ingozi ye-cerebrovascular, i-concussion sequela, i-dyspnea ebangelwa yi-anesthesia kunye nezifo zemiphunga kunye I-myocardial ischemia ebangelwa zizifo ezahlukahlukeneyo zentliziyo. Inxalenye yekhonkco lothutho lwe-electron kwi-mitochondria, i-cytochrome c ithathwa njengeyona nto isebenzayo esetyenziswa kwi-low-level laser therapy (LLLT), eyandisa umsebenzi we-metabolic kwaye ikhulula amandla amaninzi kunyango. iiseli ukulungisa izicubu.Ibonisa umsebenzi we-peroxidase nge-oxidation yabaxhasi be-electron abahlukeneyo njenge-2,2-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) (ABTS), i-2-keto-4-thiomethyl butyric acid kunye ne-4 -i-aminoantipyrine.Isetyenziswa njengomlamli obalulekileyo kwi-apoptotic pathways.Besijonge phambili ekwenzeni ubudlelwane beshishini obunempumelelo kunye nabathengi abatsha kwihlabathi liphela kungekudala.Sijonge phambili kumbuzo wakho kunye ne-odolo.


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